![]() Next, the same series of results is displayed for the Drug 6-MP group. Then, we can visualize several curves, including the survival distribution function (SDF, or survivor function, or reliability function), bounded by the confidence intervals. ![]() The next tables give the mean and median survival time and the respective confidence intervals. It contains the results of the Kaplan-Meier analysis with several key indicators such as the Survival distribution function. It starts with the Control group.įirst, the Kaplan-Meier table is displayed. Then XLSTAT displays results specific to each group. The first table displays a summary of the data for each group: Interpreting the results of a Kaplan-Meier analysis The results will then be displayed on a new Excel sheet. The computations begin once you have clicked on OK. In the Charts tab, activate the charts you wish to display, and choose the symbol you want to use to represent Censored data. The Filter option allows you to select precisely the groups on which you wish to perform the analysis. Activate the Compare option so that the comparison tests are computed. Thus XLSTAT will take into account the information whether the patient belongs to the control or the treated group. In the Data options tab, activate the By group analysis and select the group information in the data field. The Status indicator describes whether a patient relapsed (event code=1) or was censored (censored code = 0) at a given time. The Time data corresponds to the durations when the patients either relapsed or were censored. Once you've clicked on the button, the Kaplan-Meier analysis box will appear. In the ribbon, select XLSTAT > Survival analysis > Kaplan-Meier analysis Only 9 of the 6-MP patients had an observed recurrence time, while the 12 others were censored. All 21 patients of the control group were observed to have a recurrence of their leukemia. Our goal is to determine if and how the drug influences the survival time, by comparing the survival curves for two groups of 21 patients, the first being treated, and the second being a control group. The data have been obtained in and represent a randomized clinical trial investigating the effect of the drug 6-mercaptopurine on remission times (in weeks) of acute leukemia patients. This tutorial will show you how to set up and interpret a Kaplan-Meier analysis in Excel including group comparison using the XLSTAT software.
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